Prulifloxacin versus levofloxacin in the treatment of chronic bacterial prostatitis. Prulifloxacin is an older synthetic antibiotic of the fluoroquinolone class undergoing clinical trials prior to a possible nda new drug application submission to the u. It should be distinguished from other forms of prostatitis such as acute bacterial prostatitis and chronic pelvic pain syndrome cpps. Men who have this type of prostatitis have an inflamed prostate but no symptoms. It is safe or dangerous to use quercetin while suffering from prostatitis. The purpose of the study was to evaluate the efficacy of a long lasting therapy with a fluoroquinolone in association with a nutraceutical supplement prulifloxacin 600 mg for 21 days and an association of serenoa repens 320 mg, lactobacillus sporogens 200 mg, arbutin 100 mg for 30 days.
Page of 33 a c c e p t e d m a n u s c r i p t indicated that it can modulate the expression of proinflammatory cytokines, the role of which is well established in chronic prostatitis 39, 40. The antibacterial spectrum is similar to that of ciprofloxacin with clear advantages in terms of antipseudomonal in vitro activity. Acute bacterial prostatitis is associated with severe, mainly gram. Elle est associee a une fievre elevee, des douleurs abdominales ou pelviennes, des nausees et une incapacite duriner.
Pain may be present in the suprapubic or perineal region, or in the external genitalia. Prostatitis describes a combination of infectious diseases acute and chronic bacterial prostatitis, cpps or asymptomatic prostatitis. Chronic bacterial prostatitis is a bacterial infection of the prostate gland. It is a prodrug which is metabolized in the body to the active compound ulifloxacin. Organisational, regulatory and methodological matters 61. Pharmacovigilance risk assessment committee prac emaprac5767902018 page 6122. Acute bacterial prostatitis abp which is associated with severe prostatitis symptoms, systemic infection and acute bacterial uti. Can quercetin be an effective treatment for prostatitis. Prostatitis is a common healthcare issue affecting 1014% of men of all ages and ethnicities. Treatment of bacterial prostatitis clinical infectious. You may only learn you have it if your doctor does a blood test that checks your prostate. The nih classification of prostatitis syndromes12 includes. Prulifloxacin versus levofloxacin in the treatment of. Prulifloxacin, the lipophilic prodrug of ulifloxacin, is a new oral fluoroquinolone with a broad spectrum of in vitro activity against various grampositive and gramnegative microorganisms.